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PubMed · 7940060

Immunosuppressive agents.

B D Kahan·R Ghobrial
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Abstract

The present success of organ transplantation is largely due to advances in immunosuppressive therapy. Progress has been made from a cytotoxic strategy associated with a high morbidity rate to a strategy that seeks to alter the activity of cells that regulate the immune response, in order to selectively dampen antidonor responses. This article presents a comprehensive review of the clinical matrix of immunosuppressive agents, which includes various combinations of pharmacologic agents tailored to minimize toxicity and to enhance efficacy.

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Antigen PresentationClinical ProtocolsGraft RejectionHumansImmunosuppressive AgentsInfectionsLymphocyte ActivationNeoplasmsRisk FactorsTransplantation ImmunologyJournal ArticleResearch Support, U.S. Gov't, P.H.S.Review

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B D Kahan, R Ghobrial. 1994. Immunosuppressive agents.. https://pubmed.ncbi.nlm.nih.gov/7940060/

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