PubMed · 7864342
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
M F James. 1994. Problem with soda lime.. https://doi.org/10.1111/j.1365-2044.1994.tb04378.x
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
In this paper, a directly compressible form of calcium lactate is introduced as a filler-binder for direct compaction of tablets. Calcium lactate is one of the most important calcium sources and has, in comparison with other organic calcium salts, a good solubility and bioavailability. Two different modifications, calcium lactate trihydrate and calcium lactate pentahydrate are described in the main pharmacopoeias. This paper describes that the compaction properties of calcium lactate pentahydrate (Puracal DC) are much better than those of the calcium lactate trihydrate (Puracal TP). Calcium lactate pentahydrate has better compaction properties than dicalcium phosphate dihydrate, even if lubricated with magnesium stearate. Moreover, as a consequence of its crystalline structure, calcium lactate pentahydrate has a low compaction speed sensitivity. This means that, in combination with its excellent flow properties, calcium lactate pentahydrate is a suitable filler-binder in tablets prepared by high-speed compaction. In a number of formulation examples it will be illustrated that tablets containing calcium lactate pentahydrate as main or additional filler-binder have a short disintegration time and a fast drug release. Directly compressible calcium lactate can be considered as a promising excipient in both pharmaceutical tablets and tablets for the nutraceutical market.
Explore the source record for details and available documents.
Seventeen olive mill wastewater (OMW) samples were characterized. For characterization of the samples, amount of total, fixed, volatile, suspended, volatile-suspended solids, COD, oil-grease, polyphenol, volatile phenol, nitrogen and reducing sugar were determined. Effects of lime treatment on the waste samples were investigated. Reduction of contents of the samples treated with the lime was described. The effect of the addition of lime on an artificial phenolic mixture was also examined.