PubMed · 7791647
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D J Williamson. 1995-06-05. Update on scleroderma.. https://doi.org/10.5694/j.1326-5377.1995.tb138555.x
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Cardiac manifestations of the CREST syndrome or limited systemic sclerosis (ISSc) are very rare. We report a case of CREST syndrome associated with sick sinus syndrome. Histopathology of cardiac muscle revealed fibrotic changes, suggesting that such changes may be pathogenetically related to CREST syndrome.
Successful orthotopic liver transplantation may reverse extrahepatic manifestations of the primary chronic liver disease. A well documented improvement of Raynaud's phenomenon, following successful liver transplantation realized for end-stage primary biliary cirrhosis, using repetitive angiological examination and capillary microscopy is presented.
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