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PubMed · 7764801

Large-scale processing of macromolecules.

S P Fulton
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Abstract

Over the past year, a number of advances have been made in the large-scale purification of macromolecules, particularly proteins. Although refinements to individual unit operations have occurred, especially in improving the speed of operation and performance of large-scale chromatographic media, a major research thrust has been the development of processes in which steps are combined or eliminated to improve operability and reduce cost.

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AdsorptionBiological ProductsBiotechnologyChemical PrecipitationChromatographyFermentationRecombinant ProteinsTechnology, PharmaceuticalJournal ArticleReview

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S P Fulton. 1994. Large-scale processing of macromolecules.. https://doi.org/10.1016/s0958-1669(05)80037-0

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