Search PubMedSearch

PubMed · 7725275

[Acute glaucoma attack].

Abstract

An acute angle-closure glaucoma is thought of as a sudden, mostly unilateral marked increase in intraocular pressure. The patient complains of strong, sometimes radiating pain as well as a reduction in visual acuity. The affected eye is severely reddened, the cornea is cloudy, and the ocular globe feels rock-hard under palpation. Immediate therapy is decisive for maintaining visual function. In an acute case, therapy should include local pressure-reducing eye drops and systemic diuretics. Surgical intervention should always be made to prevent repeated occurrence and as a prophylaxis in the partner eye.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

H J Kaiser. 1995. [Acute glaucoma attack].. https://pubmed.ncbi.nlm.nih.gov/7725275/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

A major role for the Fas pathway in acute graft-versus-host disease.

Recent studies have suggested a role for the Fas pathway in the wasting syndrome associated with lpr-->wild-type bone marrow transplants. To directly examine whether Fas ligand has a major role in the development of acute graft-vs-host disease (GVHD), Fas ligand-deficient (gld) mice were used as donors and C3H/HeJ x C57BL/6F1 as recipients in the parent-into-F1 model of acute GVHD. Transplantation of C3H/gld spleen cells induced significantly less host lymphoid depletion and was associated with less antihost cytotoxic activity in vitro when compared with wild-type C3H donor cells. The reduced depletion of host lymphocytes was explained by both impaired antihost T cell cytolytic activity and by reduced expansion of gld donor T cells in F1 recipients. These findings not only indicate that the Fas ligand is an important effector molecule in acute GVHD, but also provide in vivo evidence supporting a role for Fas/Fas ligand interactions in T cell expansion and maturation.

Acute Disease

Induction of gammadelta T cells during acute murine infection with Toxoplasma gondii.

The importance of the host gammadelta T cell response to microbial pathogens is not yet fully understood. We report that inbred mice infected with T. gondii developed a gammadelta T cell proliferative response to parasite Ag. Mice depleted of either the alphabeta or gammadelta TCR were found to be significantly more susceptible to infection than the parent mouse strain. Proliferation of gammadelta T cells was observed in mice deficient in the TCR-alphabeta in response to UV-irradiated parasites. These T cells lyse parasite-infected syngenic macrophages. Adoptive transfer of these gammadelta T cells into beta2 microglobulin-deficient mice that have been depleted of both CD4+ and NK cells prolongs survival against acute parasite challenge when compared with nontransferred controls. The gammadelta T cells isolated from infected alpha -/- mice express a 10-fold increase in mRNA and produce high titers of IFN-gamma. These data suggest that gammadelta T cells may play an important role in the early host response to infection with T. gondii.

Acute Disease