Search PubMed⌕ Search

PubMed · 7597338

[Surgery for epilepsy].

Abstract

Surgical treatment of epilepsy is reserved for patients refractory to maximal doses of antiepileptic drugs. The success of surgery depends on the pre-surgical diagnosis, that is based in clinical history, neurological examination, electroencephalography, neuropsychological examination, Wada test and neuro imaging (basically magnetic resonance). In this way, the epileptogenic focus is precisely located and unsuspected accompanying lesions are frequently detected. The surgical procedure consist in the removal of the epileptogenic focus and the associated brain lesions (usually present). The most frequent procedures are over the temporal lobe (75%) and secondly the epileptogenic focus removal. Less frequent procedures are hemispherectomies and callosotomies. Organic lesions such as low malignancy grade tumors, embryonic developmental failures, hippocampal sclerosis are associated to temporal epilepsy in up to 80% of cases. Ninety percent of patients get rid or have a significant reduction in seizures after surgery and 10% do not experience changes.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

M G Campos. 1994. [Surgery for epilepsy].. https://pubmed.ncbi.nlm.nih.gov/7597338/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Gender effects on callosal thickness in scaled and unscaled space.

Some empirical data suggest that sexual dimorphisms in callosal morphology exist, but findings are not consistently replicated across laboratories. We applied novel computational surface-based methods to encode callosal thickness at high spatial resolution. We further examined whether callosal thickness and related gender effects are influenced by brain size adjustments achieved through data scaling. Significant gender differences were absent in scaled data, and women showed no regional thickness increases compared with men (in either scaled or unscaled data). In unscaled data, men exhibited significantly greater callosal thickness in a number of regions that may be attributable to larger brain dimensions in men. Alternatively, given their regional specificity, the observed differences in unscaled callosal thickness may contribute to gender-specific cognition and behavior.

Corpus Callosum↗

Corpus callosum hematoma secondary to isolated inferior sagittal sinus thrombosis.

A 45-year-old female was admitted with headache and vomiting. Cranial computed tomography (CT) demonstrated a callosal hematoma. Magnetic resonance imaging (MRI) showed no venous flow and thrombus replacing the inferior sagittal sinus (ISS) lumen. Under appropriate medical treatment and close follow-up she recovered quickly and, after 2 years, was doing well with corpus callosum infarcts. Isolated inferior sagittal sinus thrombosis is an extremely rare condition with only one previously reported case in the literature. Although it is very rare, isolated inferior sagittal sinus thrombosis should be considered in the differential diagnosis of non-traumatic corpus callosum hematoma.

Corpus Callosum↗

Core hypothermia in multiple sclerosis: case report with magnetic resonance imaging localization of a thalamic lesion.

Hypothermia is a rare condition in multiple sclerosis (MS). We report on a patient with a long-standing secondary progressive MS and six episodes of recurring hypothermia down to 29.9 degrees C with associated hypotension, bradycardia, coagulopathy and electrolyte dysequilibrium. Magnetic resonance imaging (MRI) demonstrated severe involvement of the corpus callosum with an associated lesion in the right posterior thalamus. These findings may link hypothermia in MS with callosal and associated thalamic pathology to Shapiro's syndrome, where agenesis of the corpus callosum and associated abnormalities are related to episodic spontaneous hypothermia. In MS, hypothermic episodes may be triggered by preceding infections, as shown in the present case.

Corpus Callosum↗