Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 7581345

Giant cell arteritis.

A W Lawton
View original source ↗Export metadata ↓

Abstract

Giant cell arteritis (GCA) is an autoimmune condition with a predilection for the arteries of the head and neck. Because GCA may lead to permanent blindness, stroke, or death, it is critically important for all health care personnel, in particular ophthalmic nurses, to know about the presentation, diagnostic methods, and treatment modalities related to this disease. Prompt intervention may save a life.

Explore related subjects

BiopsyBlindnessGiant Cell ArteritisHumansPerioperative NursingJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

A W Lawton. 1995. Giant cell arteritis.. https://pubmed.ncbi.nlm.nih.gov/7581345/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1995

[Rheumatoid arthritis, neutropenia and splenomegaly: the Felty syndrome].

HISTORY AND FINDINGS: A 59-year-old asymptomatic man, first diagnosed to have rheumatoid arthritis 27 years ago, was admitted to hospital because of splenomegaly and neutropenia, first noted 2 years ago. Physical examination confirmed splenomegaly and also revealed pretibial hyperpigmentation, but no evidence of active rheumatoid arthritis. EXAMINATIONS: Biochemical tests showed relative and absolute neutropenia (white blood cell count 2200/microliters; 1% neutrophils), thrombocytopenia and polyclonal hypergammaglobulinaemia. He also had increased erythrocyte sedimentation rate (38/92), a high titre of rheumatic factor (2128 IU/ml) and increased circulating immune-complexes (74%). Thoracic and abdominal computed tomography provided no evidence of malignant tumor. The spleen measured 15 x 7 x 10 cm. Bone-marrow biopsy from the iliac crest revealed abnormal maturation of granulopoiesis and marked lymphoid infiltration. The clinical triad of rheumatoid arthritis, splenomegaly and neutropenia are diagnostic of Felty's syndrome. As the patient was asymptomatic there was no indication for treatment. CONCLUSION: Felty's syndrome is a rare condition demanding considerable effort in differential diagnosis.

Biopsy↗