Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 7155998

Paramunity after oral immunization.

H Raettig
View original source ↗Export metadata ↓

Abstract

Previously, we have proposed the term of paramunity which represented the whole nonspecific defence reactions. Now, we experimentally have demonstrated the importance of an oral polybacterial vaccine in the local defence of the intestine against Salmonella or an enterovirus. The role of interferon was also discussed.

Explore related subjects

Administration, OralAnimalsBacterial VaccinesEnterobacteriaceae InfectionsEnterovirus InfectionsHumansImmunityImmunity, InnateImmunizationIntestinal DiseasesMiceMice, Inbred StrainsJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

H Raettig. 1982. Paramunity after oral immunization.. https://pubmed.ncbi.nlm.nih.gov/7155998/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

Adjuvanted oral vaccines should not induce allergic responses to dietary antigens.

Oral vaccines may contain adjuvants which might elicit allergies against dietary proteins. Four antigens were used to measure such an effect--ovalbumin, soya bean protein, lactalbumin and gluten. Neither guinea pigs nor mice showed IgE responses after oral administration of adjuvanted vaccines containing lactalbumin and gluten. No IgE responses were detected in mice with any of these antigens after oral immunization, but, in the guinea pig, nine out of 18 animals reacted to either ovalbumin or soya bean protein and none reacted to lactalbumin and gluten. It is concluded that the risk of allergy induction against normal dietary proteins is low but such tests should be applied to potential adjuvanted oral vaccines to measure any possible contraindication, especially with atopic individuals.

Administration, Oral↗