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PubMed · 7118361

Correlation between initial blood pressure and blood pressure decrease after weight loss: A study in patients with jejunoileal bypass versus medical treatment for morbid obesity.

K H Stokholm·P E Nielsen·F Quaade
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Abstract

Blood pressure (BP) was followed simultaneously with body weight in 134 morbidly obese patients randomized to either jejunoileal bypass (101 patients) or dietary treatment (33 patients). After a median observation time of 24 months (range 12-48 months) body weight fell significantly from a median of 124.0 kg to 81.2 kg in the jejunoileal bypass patients whilst median BP decreased significantly from 140/85 mmHg to 120/80 mmHg. In the patients treated with diet, body weight decreased significantly from a median of 129.0 kg to 119.0 kg after a median observation time of 18 months (range 9-36 months) whereas the median BP of 140/90 mmHg was unaffected. The fall in BP after weight loss was significantly positively correlated with the height of BP before the weight loss. The correlation could not be explained by a greater weight loss in the patients with initially high BP. Furthermore, a significantly positive correlation between BP changes and body weight changes was demonstrated, but this correlation was lesser than the above-mentioned. The study shows that the beneficial effect of a weight loss upon BP in obese patients is greater the higher the initial BP is, but also that a normal BP is only little affected and explained mainly by cuff artifact.

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AdultBlood PressureBody WeightFemaleHumansIleumJejunumMaleMiddle AgedObesityClinical TrialJournal ArticleRandomized Controlled Trial

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K H Stokholm, P E Nielsen, F Quaade. 1982. Correlation between initial blood pressure and blood pressure decrease after weight loss: A study in patients with jejunoileal bypass versus medical treatment for morbid obesity.. https://pubmed.ncbi.nlm.nih.gov/7118361/

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