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Acute fluoride toxicity.

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K W Stephen, W J Collins, D R McCall, T K Watkins. 1982-11-02. Acute fluoride toxicity.. https://doi.org/10.1038/sj.bdj.4804930

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Combined effects of carbon dioxide laser and fluoride on demineralized primary enamel: an in vitro study.

This in vitro study aimed at evaluating the efficacy of a CO(2) laser (10.6 microm) alone or combined with acidulated phosphate fluoride (APF) on the inhibition of lesion progression in primary enamel. The specimens were treated with/without CO(2) laser and/or APF and submitted to pH cycling. Microhardness analysis was performed and the enamel mineral loss values were obtained. The groups treated with laser and/or APF presented lower mineral loss when compared to the control group (p < 0.05). Laser irradiation alone or combined with APF decreased lesion progression in primary enamel. However, the combined treatment did not show any significant additional effect.

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Variation in surface topography of different NiTi orthodontic archwires in various commercial fluoride-containing environments.

OBJECTIVES: The surface topography can affect the friction behavior between an orthodontic wire and brackets during clinical applications. The purpose of this study was to investigate the influence of a fluoride-containing environment on the surface topography variations of different nickel-titanium (NiTi) orthodontic archwires. METHODS: Four different NiTi commercial orthodontic archwires were immersed in fluoride mouthwashes and in artificial saliva with the addition of commercial fluoride toothpastes or prophylactic gels for a 28-day period. Atomic force microscopy (AFM) was used to measure the three-dimensional surface topography of NiTi archwires before and after the immersion tests. Two-way analysis of variance (ANOVA) was used to analyze the surface roughness variance (including DeltaR(a), DeltaR(ms), and DeltaR(z)) with the archwire manufacturer and immersion test environment as the factors. RESULTS: Both the archwire manufacturer and immersion environment had a significant influence on DeltaR(a), DeltaR(ms), and DeltaR(z) (manufacturer: P<0.05; environment: P<0.0001). Regardless of the archwire manufacturer, no statistically significant difference in DeltaR(a) (<70 nm), DeltaR(ms) (<90 nm), and DeltaR(z) (<450 nm) was observed on the tested NiTi archwires in lower fluoride-containing (<2500 ppm) environments, including the various fluoride mouthwashes and the artificial saliva added with fluoride toothpastes. In artificial saliva added with high fluoride prophylactic gel (around 17,000 ppm), a significant increase in DeltaR(a) (around 120-250 nm), DeltaR(ms) (around 140-320 nm), and DeltaR(z) (around 770-1410 nm), i.e. increasing the surface roughness, was observed on the tested NiTi archwires. SIGNIFICANCE: The variation in the surface topography of the NiTi orthodontic archwires in the commercial fluoride-containing environments should be taken into consideration when the friction between the archwire and bracket is a clinical concern.

Acidulated Phosphate Fluoride↗

Comparison of frictional resistance after immersion of metal brackets and orthodontic wires in a fluoride-containing prophylactic agent.

INTRODUCTION: In this study, we investigated and compared the levels of frictional resistance between metal brackets and orthodontic wires after immersion in an acidified phosphate fluoride (APF) agent. METHODS: Three types of mandibular incisor stainless steel metal brackets with beta-titanium alloy wire (TMA), heat-activated nickel-titanium wire (Ni-Ti), and 2 sizes of stainless steel wires (SSW) were immersed in 0.2% APF and pH 6.75 artificial saliva solutions for 24 hours. The study included 480 bracket-wire specimens. The frictional resistance was measured on an EZ-test machine (Shimadazu, Tokyo, Japan) with a 5-N load cell. An Alastik (Quik-Stik Clear, A-1 Alastik, 3M Unitek, Monrovia, Calif) module ligated to the bracket was attached to the crosshead of the machine and pulled at a speed of 10 mm per minute for a distance of 5 mm. A completely randomized 1-way ANOVA was used to test for significant differences among the 3 bracket/wire specimens after immersion in 0.2% APF and pH 6.75 artificial saliva solutions. This was followed by the Student-Newman-Keuls multiple comparison of means ranking at P <.05 to determine differences between the groups. RESULTS: In the APF-immersed group, the static frictional force was greater than the kinetic frictional force. The frictional forces of the orthodontic wires had statistically significant differences (P <.05) in this progressive order: TMA, Ni-Ti, and SSW. Similar frictional force results were obtained in the pH 6.75 saliva group (P <.05). The frictional force values of the APF group were higher than those of the pH 6.75 saliva group (P <.05). CONCLUSIONS: This study demonstrates that the frictional forces of orthodontic brackets and wires are influenced by contact with fluoride-containing solutions.

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