PubMed · 687482
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M Calabresi. 1978. Left ventricular apical thin point.. https://doi.org/10.1136/hrt.40.7.823
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There are an increasing number of patients with moderate to severe pulmonary regurgitation who develop right ventricle dysfunction, with associated symptoms of fatigue and exercise intolerance, after surgical repair of tetralogy of Fallot. Critical longitudinal follow-up of these patients is needed, with assessment by clinical and laboratory studies of right ventricular size, function, and exercise capability. Pulmonary valve replacement is recommended before significant right ventricular dysfunction occurs. The search for an ideal valve to use in this condition continues.
The left ventricular ejection fraction (LVEF) is an important clinical indicator of the cardiac function and long-term outcome for patients with coronary artery disease. A biomechanical model of the left ventricle was developed to quantitatively predict post-revascularization LVEF based on noninvasive magnetic resonance imaging. The myocardium was categorized into normal, hibernating, and infarcted regions from the ventricular short-axis images. Assuming that hibernating tissue would potentially regain contractility after revascularization, the expected maximum post-revascularization LVEF was calculated for four patients with chronic left ventricular dysfunction. The predictions were within three ejection fraction points of the follow-up LVEFs. This model may be useful to estimate the outcome and efficacy of revascularization plans.
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