Fever: its history, cause, and function.

E Atkins

PubMed · 6758374

Fever: its history, cause, and function.

Abstract

Concepts of fever from Hippocrates to the present are briefly outlined and compared with current ideas of the pathogenesis of fever. Evidence is presented that endogenous pyrogen, the hormone that elevates body temperature, is identical with lymphocyte-activating factor, a monokine that stimulates lymphocyte proliferation and function.It now appears that inflammation and fever are closely interrelated phenomena that are modulated by a single hormone and that have been selected by evolution to protect the host against infection.

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Amines Animals Biological Evolution Fever History, 18th Century History, 19th Century History, 20th Century History, Ancient Humans Inflammation Interleukin-1 Monocytes Prostaglandins Pyrogens Historical Article Journal Article

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E Atkins. Fever: its history, cause, and function.. https://pubmed.ncbi.nlm.nih.gov/6758374/

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