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Focused array hyperthermia applicator: theory and experiment.

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W Gee, S W Lee, N K Bong, C A Cain, R Mittra, R L Magin. 1984. Focused array hyperthermia applicator: theory and experiment.. https://doi.org/10.1109/tbme.1984.325368

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Antenna arrays in the SIGMA-eye applicator: interactions and transforming networks.

OBJECTIVES: In multiantenna applicators such as the SIGMA-60 or SIGMA-Eye, which consist of 4 or 12 pairs of antennas shunt to 4 or 12 amplifiers ("antenna couplets"), phases and amplitudes in the feed points of these antennas under certain conditions can significantly differ from the values selected at the multichannel amplifier (forward parameters), mainly due to coupling. In the SIGMA-Eye, this interaction is particularly affected by the transforming networks between the generators and the feed points, thus hampering the control of the feed point parameters. In this work, we perform measurements at existing applicators, present a formalism to describe the facts numerically, and investigate modifications of the transforming networks to improve the performance. METHODS AND MATERIALS: We prepared an experimental setup for the SIGMA-Eye applicator that is fed by forward waves of a 12-channel amplifier system. In this setup, we made the water bolus, the interior of the tissue-equivalent phantom, and the entire transforming network accessible for measuring probes. Then, we constructed various alternative transforming networks such as Pawsey loops, LC matching networks, and power dividers and compared them with the original matching network of the SIGMA-Eye applicator. In particular, we utilized a high-resistive probe to determine the disturbances and influences caused by some channels with respect to some selected feed points of the SIGMA-Eye dipoles. RESULTS: In the original SIGMA-Eye applicator, the influences of coupling channels on the phases and voltages in the feed point of a particular antenna are largest for adjacent longitudinal channels. Here, the +/- 10 degrees phase shift and +/- 30% voltage change were observed if the reference channel (i.e., the disturbed channel) and disturbing channel are equally powered. The changes eminently increased to -30 degrees to + 100 degrees phase shift and -80% to +50% voltage change if the reference channel is fed with much lower power (four to eight-fold) than the disturbing channel. The disturbance from distant channels is less but still significant, reaching shifts of -10 degrees to +50 degrees and -50% to +20%, respectively. Using Pawsey loops instead of the original ferrite rings in the SIGMA-Eye network, the efficacy of the baluns was improved by a more than a factor of 4. Using an LC matching network, dependencies on frequency and external arrangements can be reduced significantly. Applying a power divider circuit, the coupling between antennas combined to one channel is considerably diminished (down to <-25 dB). CONCLUSION: Coupling between resonators (pairs of antennas including the matching network) reduces the control of the SIGMA-Eye applicator, i.e., it causes deviations between the selection of forward parameters at the amplifier and the total actual parameters in the feed points of the antennas. Modified transformation networks can improve the control, in particular by reducing sheath currents and asymmetries. There is a linear but variable relationship between selected (amplifiers) and actually given (feed points) parameters. This linear mapping (described by a matrix) and its characteristics need further investigation.

Hyperthermia, Induced↗

Temperature measurement errors with thermocouples inside 27 MHz current source interstitial hyperthermia applicators.

The multielectrode current source (MECS) interstitial hyperthermia (IHT) system uses thermocouple thermometry. To obtain a homogeneous temperature distribution and to limit the number of traumas due to the implanted catheters, most catheters are used for both heating and thermometry. Implications of temperature measurement inside applicators are discussed. In particular, the impact of self-heating of both the applicator and the afterloading catheter were investigated. A one-dimensional cylindrical model was used to compute the difference between the temperature rise inside the applicators (deltaTin) and in the tissue just outside the afterloading catheter (deltaTout) as a function of power absorption in the afterloading catheter, self-heating of the applicator and the effective thermal conductivity of the surrounding tissue. Furthermore, the relative artefact (ERR), i.e. (deltaTin - deltaTout)/deltaTin, was measured in a muscle equivalent agar phantom at different positions in a dual-electrode applicator and for different catheter materials. A method to estimate the tissue temperature by power-off temperature decay measurement inside the applicator was investigated. Using clinical dual-electrode applicators in standard brachytherapy catheters in a muscle-equivalent phantom, deltaTin is typically twice as high as deltaTout. The main reason for this difference is self-heating of the thin feeder wires in the centre of the applicator. The measurement error caused by energy absorption in the afterloading catheter is small, i.e. even for materials with a high dielectric loss factor it is less than 5%. About 5 s after power has been switched off, Tin in the electrodes represents the maximum tissue temperature just before power-off. This delay time (t(delay)) and ERR are independent of Tin. However, they do depend on the thermal properties of the tissue. Therefore, ERR and t(delay) and their stability in perfused tissues have to be investigated to enable a reliable estimation of the tissue temperatures around electrodes in clinical practice.

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