In vitro complement consumption by contrast materials and analogues: reactors vs. nonreactors.

R L Siegle; P Lieberman; M C Rice

doi:10.1097/00004424-198307000-00018

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PubMed · 6618830

In vitro complement consumption by contrast materials and analogues: reactors vs. nonreactors.

R L Siegle·P Lieberman·M C Rice

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Abstract

Blood samples from previous contrast reactors and nonreactor controls were incubated with diatrizoate and several contrast analogues. Total complement levels were assayed. All the agents caused complement activation generally proportional to their concentration. Reactors' sera responded to lower concentrations of contrast or analogues than did control sera. Such studies might be of value in predicting contrast reactors.

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Acetamides Aminobenzoates Complement Activation Contrast Media Diatrizoate Drug Hypersensitivity Humans In Vitro Techniques Metrizamide meta-Aminobenzoates Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

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R L Siegle, P Lieberman, M C Rice. In vitro complement consumption by contrast materials and analogues: reactors vs. nonreactors.. https://doi.org/10.1097/00004424-198307000-00018

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