Search PubMedSearch

PubMed · 6544551

[A study on the difference factor in computerized infrared difference spectroscopy].

Abstract

The source did not provide an abstract. Follow the original record for more information.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

X He, Q Y Gao. 1984. [A study on the difference factor in computerized infrared difference spectroscopy].. https://pubmed.ncbi.nlm.nih.gov/6544551/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin.

Rapid cell death, as evidenced by a decrease in cell counts, was observed when molt-4-lymphoblastoid cells, a human leukemia cell line, were exposed to holotransferrin (12 microM) and dihydroartemisinin (1-200 microM). Incubation with either compound alone was significantly less effective. Significantly less cell death was observed when normal human lymphocytes were exposed to a combination of these 2 drugs. Probit analysis of dose-response functions shows that the drug combination is approximately 100 times more effective on molt-4 cells than lymphocytes (LD50s for molt-4 and lymphocytes were 2.59 microM and 230 microM, respectively). This drug combination may provide a novel approach for cancer treatment.

Artemisinins

Bioconversion of arteannuin B to artemisinin.

Arteannuin B, which co-occurs with artemisinin, the potent antimalarial principle of the Chinese medicinal herb Artemisia annua (Asteraceae), has been converted to the latter using crude and semi-purified cell-free extracts of the leaf homogenates of the plant. Detection procedures to quantitate this bioconversion, including one that is novel which uses gcms, are detailed.

Artemisinins

[Early treatment of attacks of pernicious malaria with artemisinine per os].

416 cases of P. falciparum cerebral malaria are treated with various anti-M drugs: mortality rate is 25% with quinacrine, 12.3%; quinine alone, and 10.1% with quinine associated to sulfonamide. During 1991-1992, artemisinin per os is used in the early treatment of 21 cases of cerebral malaria, in according to propose a regimen practicable at primary health care units, where parenteral injection is sometimes unavailable: coma clearance after 14-21 hours in 100%, fever clearance after 54-97 hours in 100%, and parasite clearance in 100% after 101 hours; no case of death is found.

Artemisinins