PubMed · 6514266
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N S Jaffe. 1984. Nucleus delivery.. https://pubmed.ncbi.nlm.nih.gov/6514266/
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We report a case of a girl with clinical features of Peters' Plus Syndrome (PPS) (association of anterior eye chamber defects; peculiar facies; cleft lip/palate; brachymelia; developmental delay; growth retardation) and documented growth hormone deficiency (height -3.5 SDS at chronological age 5 years 8 months; low growth factors; bone age delay; growth velocity 4.4 cm/year (<3rd centile); and peak growth hormone levels of 1.7 and 4.7 ng/ml by clonidine and insulin provocative testing, respectively). Treatment with recombinant human growth hormone (0.3 mg/kg/week) resulted in a dramatic increase in growth velocity, increasing the height from -3.5 to -1.5 SDS over 2.3 years of therapy, indicative of an excellent response. Growth retardation is a known association in PPS: a condition that includes other midline facial defects. This case supports a role for GHD in the pathogenesis of the short stature observed in these children; demonstrates the efficacy of GH treatment; and further reinforces the relationship of pituitary anomalies with common congenital defects.
Ocular trauma is readily investigated by ultrasound, which is of particular value when the light conducting media are opacified by haemorrhage or other injury. In this situation, direct visualization of the ocular contents by ophthalmoscopy is difficult or impossible. Severe complications are treated by microsurgical techniques, and ultrasound evaluation represents the only practicable method of examination for surgical planning. This review illustrates the grey-scale (B scan or two-dimensional) features of the traumatized eye and describes the examination technique.
Bimanual microincision phacoemulsification entails the removal of the crystalline lens through 2 1.2 mm incisions. Infusion is provided through a separate irrigating handpiece, and phacoemulsification and aspiration are performed through a sleeveless phacoemulsification needle. We describe a technique for refractive lens exchange using bimanual microincision phacoemulsification. Capsulorhexis formation, cortical cleaving hydrodissection, lens extraction in the iris plane, and residual cortex removal are performed through the microincisions. This technique offers improved surgeon control throughout the procedure and added safety by maintaining continuous pressurization of the eye while removing the lens far from the posterior capsule.