Search PubMed⌕ Search

PubMed · 651234

[Postural glaucoma (author's transl)].

Abstract

Three patients with different eye problems show pathological intraocular pressure in the supine position, while the pressure in the seated position was normal. In all three cases normalisation of intraocular pressure in the supine position could be achieved by treatment with Pilocarpine and other antiglaucomatous agents. Unfortunately one cases showed an aggravation of the visual acuity and visual fields. The term low tension glaucoma is discussed.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

U W Wüthrich. 1978. [Postural glaucoma (author's transl)].. https://pubmed.ncbi.nlm.nih.gov/651234/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

New purines with antiplatelet activity.

Four purine-2,6-diamines, 4a, b, 5a, b, nineteen N-(purin-2-yl)benzenecarboxamides 6a-q, 7b, and one N-(purin-2-yl)-2-furanecarboxamide 8 were prepared for the first time and tested for their inhibition of blood platelet aggregation. Six compounds, 6a, b, h, m, o, p, inhibited the platelet aggregation induced by collagen with IC(50 )values between 3 and 10 micromol/L in the Born test. ADP, PAF, and adrenaline were used as specific aggregation inducers to examine the mechanism of the anti-aggregating activity. An astonishing pattern of activities in the nanomolar, with 6m, 7b, 8 and even subnanomolar range, with 6b, was observed. Compound 6b inhibited the platelet aggregation induced by ADP with an IC(50) = 0.45 nM (6m: 3.5 nM; 8: 30 nM). Compound 7b showed an antagonism against the inducer adrenaline with an IC(50) = 1.8 nM (6o: 20 nM; 8: 30 nM). The strongest antagonism against PAF was observed with 7b showing an IC(50) = 1 nM (6b: 35 nM; 8: 74 nM).

Epinephrine↗