Search PubMedSearch

PubMed · 6428930

Decrease of exercise-induced asthma after physical training.

Abstract

Exercise-induced asthma (EIA) is a multifactorial disease induced by cooling and drying of the airways. Mediator release or vagal stimulation, or both, may transmit the reaction to bronchial muscles. Premedication with beta 2-aerosol before exercise has the best preventive effect, although disodium cromoglycate (DSCG) or atropine prevent EIA in about 50% of the patients. EIA is provoked when the anaerobic threshold is passed. Training with high load interval exercise after premedication increased the anaerobic threshold in three groups of children, and a significant decrease in EIA was recorded, while a non-training control group showed no changes.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

M Arborelius, E Svenonius. 1984. Decrease of exercise-induced asthma after physical training.. https://pubmed.ncbi.nlm.nih.gov/6428930/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Effect of Rb+ on cromakalim-induced relaxation and ion fluxes in guinea pig trachea.

The effects of cromakalim, verapamil and salbutamol have been examined in guinea pig trachealis smooth muscle in both Krebs physiological salt solution and Krebs solution where K+ has been replaced by Rb+. Cromakalim-induced relaxation in the presence of Rb+ was reduced in extent and became transient, whilst the relaxation response to verapamil was enhanced and that to salbutamol unaffected. The transient relaxation occurring in Rb+ was blocked by quinidine and glibenclamide. The presence of extracellular Rb+ also prevented cromakalim-stimulated efflux of both 86Rb+ and 42/43K+. There was, however, no effect on cromakalim-stimulated 86Rb+ uptake. It is proposed that cromakalim is opening two populations of potassium channel in guinea pig tracheal smooth muscle, one of which is susceptible to blockade by Rb+ and one of which is not. The latter channel appears to play the dominant role in cromakalim-stimulated uptake, and is responsible for the transient relaxation response in the presence of rubidium, whilst the former is responsible for the maintained relaxation.

Albuterol