PubMed · 6344708
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S Rapoport, P Zyman. 1983. Captopril and central nervous system effects.. https://doi.org/10.7326/0003-4819-98-6-1023_1
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A 19-month-old girl presented with severe neurologic symptoms associated with exanthem subitum. Human herpesvirus type 7 (HHV-7) DNA was detected in the CSF and serum, and supported by serologic studies. The patient was diagnosed with encephalopathy due to an acute HHV-7 infection. Neuron-specific enolase in the CSF was strongly elevated during the acute stage of infection, suggesting that the encephalopathy was due to viral invasion of the brain.