PubMed · 5697123
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
I Testa-Bappenheim. 1968-10-06. [Karyotype and behavior].. https://pubmed.ncbi.nlm.nih.gov/5697123/
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
On the basis of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2), 20 male students were separated in low (LP) versus high (HP) subjects with psychopathic tendencies. Pictures from the Ekman and Friesen series were used in an event-related potentials study to investigate the neurophysiological correlates of the emotional deficit described in psychopathy. Subjects were confronted with a visual oddball design, in which they had to detect, as quickly as possible, deviant happy, sad or fearful faces amongst a train of standard stimuli (neutral faces). Behavioral results suggest that LP subjects are more efficient in the detection of emotional deviant faces. This emotional deficit was neurophysiologically indexed, in HP subjects, by a decreased N300 component, which is supposed to be particularly sensitive to affective features of stimuli rather than to physical characteristics. Moreover, independently of the nature of the deviant faces, the P3a component shows an earlier latency in the HP group as compared to the LP group, whereas the reversed pattern was shown for the P3b component. Implications of these results were discussed.
There is emerging evidence of gene-environment interaction effects on conduct problems, both from adoption studies and from a study using a measured genotype. An association between non-violent family dysfunction and conduct problems has also been reported, although not in the context of gene-environment interaction studies. The aim of this study was to examine the interaction of genes and family dysfunction in contributing to conduct problems in young people. Parents of 278 monozygotic and 378 dizygotic twin pairs, aged 5-18, from the CaStANET birth cohort twin register were questioned about zygosity, conduct problems and family environment. Using structural equation modeling we tested for main and interactive effects of genes and family dysfunction modelled as an environmental "moderator variable". Both main and gene-environment interaction effects were highly significant. It was concluded that a risk genotype conferring susceptibility to family dysfunction is responsible for most of the variance in antisocial symptoms in childhood and adolescence.
Within the past several years, neuroimaging research on personality disorders has begun to develop. Personality disorders can be thought of as trait-like dysfunctional patterns in cognitive, affective, impulse control, and interpersonal domains. These domains of dysfunction have been linked to specific neural circuits. Developments in brain imaging techniques have allowed researchers to examine the neural integrity of these circuits in personality-disordered individuals. This article reviews the neuroimaging literature on borderline personality disorder, antisocial personality disorder (including psychopathy) and schizotypal personality disorder. Functional and structural studies provide support for dysfunction in fronto-limbic circuits in borderline and antisocial personality disorder, whereas temporal lobe and basal striatal-thalamic compromise is evident in schizotypal personality disorder.