PubMed · 5553054
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
1971. Cephalexin.. https://pubmed.ncbi.nlm.nih.gov/5553054/
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
Cephalosporin antibiotics were separated on thin layer plates impregnated with transition metal ions, Mn(2+), Fe(2+), Co(2+), Ni(2+) and Cu(2+), using different concentrations. Various solvent systems were developed for the study and were used for separation of these analytes. Impregnation was observed to have an effect on hR(F) values, removed tailing of analytes and improved the resolution. The results have been discussed for each metal ion and compared, and the best conditions of separation have been identified. Activation time of thin layer plates impregnated with 0.1% FeSO(4) was found to affect both hR(F) values and resolution of cephalosporins. New solvent systems are reported for both normal phase and reversed-phase TLC.