PubMed · 5248574
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R H Miller. 1968. Denture burning, dryness.. https://pubmed.ncbi.nlm.nih.gov/5248574/
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Nested polymerase chain reaction (PCR) was performed to detect the presence of Helicobacter pylori in tongue mucosa in 268 patients divided into four groups according to their diagnosis: 87 with atrophic glossitis, 37 with benign migratory glossitis and 144 with burning mouth syndrome (BMS). The latter group was subdivided according to anatomic site of burning sensation: subgroup A (54 patients) with complaints limited to tongue and subgroup B (90 patients) with burning sensations in other parts of oral mucosa. H. pylori was found in 43 samples (16%). Bacteria were significantly less present in tongue mucosa affected with benign migratory glossitis compared with atrophic glossitis and BMS (P=0.025). This difference was more obvious when compared with atrophic glossitis only (P=0.006). Mucosal changes in these conditions might make the oral environment more acceptable for H. pylori colonization compared with normal mucosa, and this mechanism may play a role in its oro-oral transmission.
BACKGROUND: The prevalence of diabetes mellitus, or DM, in the United States is increasing steadily. The increasing longevity of the American population and more effective diagnostic protocols mean that the dental practitioner will be treating an increasing number of patients with the disease. METHODS: The authors present relevant information about DM, including a recently revised nomenclature system, pathophysiology, complications, new diagnostic criteria, medical and dental management considerations, and associated oral conditions. CONCLUSIONS: There are many important medical and dental management issues that dentists should consider when treating patients with DM. CLINICAL IMPLICATIONS: The information presented in this report should help general dentists deliver optimum treatment to patients with DM.
There is controversy about the role of contact allergy in the pathogenesis of oral lichen planus (OLP) and the burning mouth syndrome (BMS). Patients with OLP or BMS might wish to pursue allergy testing in hopes of identifying the cause of their disease. Although patch testing in these conditions might provide useful information, one risks discovering allergens of uncertain relevance. We asked 2 experts in the field to discuss their approaches to evaluation and management of OLP and BMS, with an emphasis on the role of patch testing.