PubMed · 5188990
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B A Campbell. 1968. Nurses dealing in wheeling.. https://pubmed.ncbi.nlm.nih.gov/5188990/
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Studies on beta-hemolytic streptococci have been carried out in 2 institutions for handicapped preschool children during the last nine-year period from 1985 to 1993. These studies were based on continuous throat cultures, 4 to 12 times a year, from 244 children including Down's syndrome and mentally retarded children in K-institution (K), and from 134 including cerebral palsy and other cerebrospinal disorders in H-institution (H). A significant difference (p < 0.05) was demonstrated in the isolation rates between K (11.1%) and H (6.4%). In K, isolation rates of beta-hemolytic streptococci ranged from 0 to 43.5%, showing a higher rate in winter (16.5%) than in summer (6.6%), and elevated-isolation rates of homologous types were demonstrate four times during the study period; i.e., type T12 in '87, type T28 in '88, type T1 in '90 and '92. In H, on the other hand, no higher rates (as to group A) were observed in winter or summer. In relation to disorders of children, the rates were 12.6% in Down's syndrome (mean age 2.7y), 10.0% in mentally retarded children (3.9y) and 6.4% in cerebral palsy or others with cerebrospinal disorders (3.3y). Down's syndrome, the youngest group, revealed the highest isolation rate of beta-hemolytic streptococci. In only two cases isolated hemologous types detected were over two times continuously.
An outbreak of measles broke out and prevailed in the Beijing Children Welfare House from March 23rd to April 27th, 1992. The 18 victims accounted for 4.8% of the whole infant population in the Welfare House, 11 of them being babies of less than 8 months. One third of the attacked babies were in bad condition and were hospitalized in the observation room. The clinical manifestations indicated that severe symptoms, more complications but favourable prognosis were characteristic of the infant patients. Based on the epidemiologic study and serological test, it was found that the outbreak and spread of the measles originated from outside the Welfare House. It was also found that the vaccinated handicapped infants exposed to natural measles were highly protected. This investigation leads to the conclusion that the cause of this measles outbreak was laid to the vacancy of planning immunization and the existence of a large number of non-protected babies.
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