PubMed · 486613
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W Grove, N Andreasen, K Halmi. 1979. Statistical salvation.. https://pubmed.ncbi.nlm.nih.gov/486613/
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Collection of data with a large field of view camera can cause problems when a small organ like the heart is to be imaged, especially when high activity is used. A simple, inexpensive mask is described that solves most of these problems.
This article describes how one company (The Dow Chemical Company) is managing the issue of increasing demands by regulatory agencies for health and environmental information. Described are: an interdisciplinary organization linked by a resource and communication network; methods of evaluating information requests and establishing priorities for response; and problems in communicating with the regulators. The need for a responsive technical dialogue between government and industry is stressed.
An improved interactive system for searching substructure and biological activity data has been developed. Features of the system include a two-level substructure search (fragment screen and atom by atom) and an expanded biological activity data base. The system operates on a file of about 150 000 compounds.