Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 4660453

[Decrease of urinary adrenalin excretion in primary corticoadrenal insufficiency].

J Crabbé·Y Vandeput·R M Blizzard
View original source ↗Export metadata ↓

Abstract

The source did not provide an abstract. Follow the original record for more information.

Explore related subjects

Addison DiseaseAdrenal Cortex HormonesAdrenal Gland DiseasesAdrenal InsufficiencyAdultAgedAntibodiesEpinephrineFemaleHumansMaleMiddle AgedNorepinephrineTuberculosis, EndocrineJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

J Crabbé, Y Vandeput, R M Blizzard. [Decrease of urinary adrenalin excretion in primary corticoadrenal insufficiency].. https://pubmed.ncbi.nlm.nih.gov/4660453/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

Steroid 21-hydroxylase is a major autoantigen involved in adult onset autoimmune Addison's disease.

An adrenal-specific protein reacting with autoantibodies in the sera of patients with adult onset Addison's disease has been purified from human adrenal glands. The protein, mol.wt. 55K, has the biochemical characteristics of steroid 21-hydroxylase and reacts on Western blots with rabbit antibodies to recombinant 21-hydroxylase. Absorption of the native human 55K adrenal protein with human adrenal autoantibodies prevented the subsequent reaction of the 55K protein with rabbit antibodies to 21-hydroxylase in Western blot analysis. In addition, human adrenal autoantibodies reacted with recombinant 21-hydroxylase expressed in yeast. These data indicate that the adrenal specific enzyme steroid 21-hydroxylase is a major autoantigen involved in adult onset autoimmune Addison's disease.

Addison Disease↗