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PubMed · 460001

Premature labour.

T R Eggers·L W Doyle·R J Pepperell
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Abstract

Intravenously administered salbutamol inhibited premature labour for at least 48 hours in 49 of 76 patients (64%), but was more effective (89%) when the cervical dilatation was less than 2 cm, and no apparent cause for the premature labour was evident. Even when premature labour complicated multiple pregnancy, hydramnios, or followed a small antepartum haemorrhage, suppression of labour could often be achieved for at least 48 hours, thus following the administration of betamethasone or the transfer of the patient to a hospital with intensive care facilities for both mother and child. Treatment with betamethasone, in addition to salbutamol, was associated with a less severe form of respiratory distress syndrome, and did not increase the risk of maternal or fetal infection, except in patients with cervical incompetence when 46.2% of such patients were infected.

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AlbuterolBetamethasoneFemaleHumansInfant, NewbornInfectionsObstetric Labor, PrematurePregnancyRespiratory Distress Syndrome, NewbornUterine Cervical IncompetenceJournal Article

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T R Eggers, L W Doyle, R J Pepperell. 1979-03-24. Premature labour.. https://pubmed.ncbi.nlm.nih.gov/460001/

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