PubMed · 4514218
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D J Krutchoff, W J Simon. 1973. How to test for bleeding time.. https://pubmed.ncbi.nlm.nih.gov/4514218/
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INTRODUCTION: Congential deficiency of factor V is a rare condition, transmitted in autosomal recessive way. Heterozygote patients generally have no symptoms, homozygotes present with spontaneous and postoperative bleedings. About one-half of patients are diagnosed in adulthood. METHODS: The presented case is a double heterozygote, which was confirmed using moleculare biological methods. The authors found many carriers in his family. CONCLUSIONS: This rare and sometimes severe disorder needs regular haematological controls. Carriers must have more attention during surgical procedures and labour, and the family doctor should be informed about there condition.
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Different types of mechanical ventricular assist devices are available for treating end stage congestive heart failure. Despite technical improvements, however, various complications are still reported for patients during mechanical support. We report our experience with intraventricular thrombolysis as a treatment for possible thrombosis of a continuous flow device that had been implanted as a bridge to heart transplantation. This approach has been demonstrated to be both effective and safe.