PubMed · 4438133
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A Gorski. 1974. [Immunologic deficits caused by abnormal phagocyte function].. https://pubmed.ncbi.nlm.nih.gov/4438133/
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This report describes clinical and laboratory features of a case of Chediak-Higashi syndrome that presented in the accelerated phase of the disorder. This female infant presented with a fever, marked neutropenia, large cytoplasmic granules in leukocytes and a constellation of features that suggested a virus-associated hemophagocytic syndrome. The clinical course was marked by limited response to the therapeutic agents that included ascorbate, cytotoxic agents and granulocyte colony-stimulating factor.
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