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Effects of different resistance exercise programs on upper limb functional recovery in postoperative breast cancer patients.

Shuo Wang·Xiang-Yu Zhou·Yi-Ying Wang·Yi-Jing Fan·Ai-Jun Du·Yu Li·Li-Zhi Zhou·Shu-Fang Zhang
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Abstract

PURPOSE: To investigate the effects of grip strength exercise combined with upper limb resistance exercise on upper limb functional rehabilitation in patients after breast cancer surgery. METHODS: A total of 111 patients who underwent either modified radical mastectomy with ALND or breast-conserving surgery with ALND were randomly assigned to a control group, an upper limb resistance exercise group, and a combined grip and upper limb resistance exercise group. Grip strength was measured at baseline, 16 weeks after intervention, and at 3- and 6-month follow-ups, while shoulder function was assessed using the Constant-Murley Scale (CMS). RESULTS: There were no statistically significant differences in grip strength or CMS scores among the groups before intervention (P&#x202f;>&#x202f;0.05). At the post-intervention, 3-month, and 6-month follow-ups, compared with the control group, both resistance training protocols significantly improved patients' joint range of motion, pain, muscle strength, total CMS score, and grip strength (P&#x202f;<&#x202f;0.05). Compared with the upper limb resistance exercise group, the combined grip and upper limb resistance exercise group demonstrated superior grip strength at the 6-month follow-up (P&#x202f;<&#x202f;0.05), as well as more significant improvements in joint range of motion, pain, muscle strength, and total CMS scores (P&#x202f;<&#x202f;0.05). CONCLUSION: A 16-week resistance exercise program effectively improves upper limb function in post-surgical breast cancer patients, with the combined grip and upper limb resistance exercise program yielding superior outcomes.

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HumansFemaleBreast NeoplasmsResistance TrainingUpper ExtremityMiddle AgedHand StrengthFollow-Up StudiesRange of Motion, ArticularRecovery of FunctionPrognosisExercise TherapyAdultMuscle StrengthMastectomy, SegmentalMastectomy, Modified RadicalBreast cancer surgeryGrip strengthProgressive resistance exerciseUpper limb functionJournal ArticleRandomized Controlled Trial

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Shuo Wang, Xiang-Yu Zhou, Yi-Ying Wang, Yi-Jing Fan, Ai-Jun Du, Yu Li, Li-Zhi Zhou, Shu-Fang Zhang. 2026-08-10. Effects of different resistance exercise programs on upper limb functional recovery in postoperative breast cancer patients.. https://doi.org/10.1016/j.suronc.2026.102531

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Journal Article; Randomized Controlled Trial resourceAdult subjectBreast Neoplasms subjectExercise Therapy subjectFemale subjectFollow-Up Studies subjectHand Strength subjectHumans subjectJournal Article subjectMiddle Aged subjectMuscle Strength subjectRandomized controlled trials study

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