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BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish-Language mHealth Adherence Support App for Spanish-Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment.

Micah A Skeens·Madeline R Peek·Bianca Franklin·Emre Sezgin·Melissa Beauchemin
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Abstract

BACKGROUND: Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver-facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note-taking features to support medication management. Spanish-speaking caregivers are frequently excluded from digital adherence interventions due to the lack of language-accessible tools. PROCEDURE: We conducted a multisite, mixed-methods usability testing of a Spanish-language version of BMT4me ("BMT4me en Español") with Spanish-speaking caregivers of children (ages 2-17 years) post-HSCT or with an oncology diagnosis on active treatment. Caregivers completed a facilitated, three-step usability session (unobtrusive observation, interactive observation, and debriefing), followed by a semi-structured interview, and then completed the system usability scale (SUS). Quantitative outcomes were summarized descriptively; qualitative data were analyzed using content analysis with constant comparison. RESULTS: Fifteen participants enrolled at each site for a total of 30 participants. Across both sites, the recruitment rate was 91%. All participants completed all parts of the study. The SUS score (M = 80.09; SD = 17.35) was above average (>68). Two key qualitative themes emerged: (1) the perceived positive impact of BMT4me on managing a serious illness and (2) the acceptance and sociocultural relevance of BMT4me for Spanish-speaking families. Caregivers also shared suggestions to add educational content and multiuser functionalities to BMT4me. CONCLUSIONS: The acceptance and perceived positive impact of the Spanish BMT4me app indicates that socioculturally relevant, Spanish mHealth interventions have strong potential to support Spanish-speaking caregivers in pediatric oncology and HSCT settings. CLINICAL TRIALS NCT: NCT06361173.

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AdolescentAdultChildChild, PreschoolFemaleHumansMaleAdherence InterventionsCaregiversFeasibility StudiesFollow-Up StudiesHematopoietic Stem Cell TransplantationHispanic or LatinoLanguageMedication AdherenceMobile ApplicationsNeoplasmsTelemedicineSpanish‐speaking caregivershematopoietic stem cell transplantationmedication adherencemobile healthusabilityJournal ArticleMulticenter StudyObservational Study

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Micah A Skeens, Madeline R Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin. 2026-07-23. BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish-Language mHealth Adherence Support App for Spanish-Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment.. https://doi.org/10.1002/1545-5017.70509

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Adherence Interventions subjectAdolescent subjectAdult subjectChild subjectChild, Preschool subjectFeasibility Studies subjectFemale subjectFollow-Up Studies subjectHispanic or Latino subjectHumans subjectJournal Article subjectMale subjectMulticenter Study subjectNeoplasms subjectObservational Study subject

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