Chronic postsurgical pain: risk assessment and mitigation.

Martin D Cheatle; Isabella Rosales; Kai-Hua Chang; Yoonjae Lee

doi:10.1097/aco.0000000000001684

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Chronic postsurgical pain: risk assessment and mitigation.

Martin D Cheatle·Isabella Rosales·Kai-Hua Chang·Yoonjae Lee

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Abstract

PURPOSE OF THE REVIEW: Chronic postsurgical pain (CPSP) and persistent postoperative opioid use (PPOU) are two of the most common complications of a number of surgical interventions, which can cause significant personal and economic negative consequences. This review outlines known and potential risk factors for CPSP and PPOU and approaches to reduce these risk factors. RECENT FINDINGS: Modifiable risk factors for developing CPSP include psychological distress, preoperative pain intensity, and perioperative opioid exposure. Although less studied, psychological comorbidities are also risk factors for PPOU. Evidence-based mitigation strategies include psychological interventions and perioperative opioid sparing. SUMMARY: A number of perioperative risk factors for developing CPSP and PPOU have been identified, and anesthesiologists should be cognizant of these risk factors and potential risk mitigation strategies. Additional prospective studies are needed to further develop easily adoptable, evidence-based interventions to reduce the incidence of CPSP and PPOU.

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Humans Postoperative Pain Chronic Pain Analgesics, Opioid Risk Factors Risk Assessment Opioid-Related Disorders Pain Management chronic postsurgical pain cognitive behavior therapy opioid sparing persistent postoperative opioid use Journal Article Review

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Martin D Cheatle, Isabella Rosales, Kai-Hua Chang, Yoonjae Lee. 2026-06-22. Chronic postsurgical pain: risk assessment and mitigation.. https://doi.org/10.1097/aco.0000000000001684

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Journal Article; Review resource Analgesics, Opioid subject Humans subject Journal Article subject Opioid-Related Disorders subject Pain Management subject Postoperative Pain subject

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