SEMPLR: an R package for transcription factor binding prediction.

Grace E Kenney; Rintsen N Sherpa; Jeremy D Burgess; Alan P Boyle; Douglas H Phanstiel

doi:10.1093/bioinformatics/btag383

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SEMPLR: an R package for transcription factor binding prediction.

Grace E Kenney·Rintsen N Sherpa·Jeremy D Burgess·Alan P Boyle·Douglas H Phanstiel

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Abstract

SUMMARY: SEMPLR is an R package that predicts transcription factor binding and variant effects using SNP Effect Matrices (SEMs), providing efficient, genome-wide scoring, enrichment testing, and visualization tools for comprehensive analysis of regulatory sequences. AVAILABILITY: Available on GitHub at https://github.com/grkenney/SEMPLR and on Bioconductor at https://bioconductor.org/packages/release/bioc/html/SEMPLR.html.

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Transcription Factors Software Polymorphism, Single Nucleotide Protein Binding Binding Sites Computational Biology Journal Article Research Support, N.I.H., Extramural

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Grace E Kenney, Rintsen N Sherpa, Jeremy D Burgess, Alan P Boyle, Douglas H Phanstiel. 2026-06-01. SEMPLR: an R package for transcription factor binding prediction.. https://doi.org/10.1093/bioinformatics%2Fbtag383

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