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PubMed · 41081605

Easy and interactive taxonomic profiling with Metabuli App.

SunJae Lee·Jaebeom Kim·Milot Mirdita·Cameron L M Gilchrist·Martin Steinegger
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Abstract

SUMMARY: Accurate metagenomic taxonomic profiling is critical for understanding microbial communities. However, computational analysis often requires command-line proficiency and high-performance computing resources. To lower these barriers, we developed Metabuli App, an all-in-one desktop application that efficiently runs taxonomic profiling locally on a consumer-grade computer. It features user-friendly graphical interfaces for custom database curation, raw read quality control (QC), taxonomic profiling, and interactive result visualization. AVAILABILITY AND IMPLEMENTATION: GPLv3-licensed source code and prebuilt apps for Windows, macOS, and Linux are available at https://github.com/steineggerlab/Metabuli-App and are archived at https://doi.org/10.5281/zenodo.15876171. Analysis scripts are available at https://github.com/jaebeom-kim/metabuli-app-analysis. The Sankey-based taxonomy visualization component is available at https://github.com/steineggerlab/taxoview for easy integration into other web projects.

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SoftwareMetagenomicsUser-Computer InterfaceJournal ArticleResearch Support, Non-U.S. Gov't

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SunJae Lee, Jaebeom Kim, Milot Mirdita, Cameron L M Gilchrist, Martin Steinegger. 2025-10-02. Easy and interactive taxonomic profiling with Metabuli App.. https://doi.org/10.1093/bioinformatics%2Fbtaf557

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