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PubMed · 4070075

Thymus carcinoid.

R Viebahn·W Hiddemann·F Klinke·D B von Bassewitz
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Abstract

A carcinoid of the thymus was studied by light- and electron-microscopy, immunohistology and flow-cytometry. The tumor showed a ribbon- and festoon-like growth-pattern with foci of necrosis, invasion of vessels and infiltration of mediastinal lymph nodes. The cytoplasma of the tumor-cells contained neuroendocrine granula and immunohistochemistry of ACTH was positive. The tumor-cells were connected by desmosomes, correlating to a pre-keratin positive immunohistology. In flow-cytometry the tumor-cells showed a near haploid DNA aneuploidy which is an extremely rare finding in solid tumors and in the few cases described indicative for treatment resistance.

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Carcinoid TumorFemaleFlow CytometryHumansLymphatic MetastasisMicroscopy, ElectronMiddle AgedNecrosisThyroid NeoplasmsCase ReportsJournal Article

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R Viebahn, W Hiddemann, F Klinke, D B von Bassewitz. 1985. Thymus carcinoid.. https://doi.org/10.1016/s0344-0338(85)80119-9

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