A Missense Substitution in Exon 2 Generates the First HLA-DQB1*04 Allele With Glutamine at Residue 52, DQB1*04:108.

Juan L&#xf3;pez-P&#xe9;rez; Francisco Javier Gil-Etayo; Ariadna Vicente Parra; Isabel Jim&#xe9;nez Hernaz; Amalia Tejeda Velarde

doi:10.1111/tan.70265

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A Missense Substitution in Exon 2 Generates the First HLA-DQB104 Allele With Glutamine at Residue 52, DQB104:108.

Juan López-Pérez·Francisco Javier Gil-Etayo·Ariadna Vicente Parra·Isabel Jiménez Hernaz·Amalia Tejeda Velarde

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Abstract

HLA-DQB1*04:108, the first HLA-DQB1*04 allele with Glutamine at residue 52 in the peptide-binding domain.

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Humans Alleles Exons Glutamine Mutation, Missense HLA-DQ beta-Chains Amino Acid Substitution Histocompatibility Testing Base Sequence HLA‐DQB1*04:108 HLA class II HLA typing next‐generation sequencing peptide‐binding domain Journal Article

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Juan López-Pérez, Francisco Javier Gil-Etayo, Ariadna Vicente Parra, Isabel Jiménez Hernaz, Amalia Tejeda Velarde. 2025. A Missense Substitution in Exon 2 Generates the First HLA-DQB1*04 Allele With Glutamine at Residue 52, DQB1*04:108.. https://doi.org/10.1111/tan.70265

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