Search PubMedSearch

PubMed · 395086

Control algorithms for artificial beta cell.

Abstract

The evolution of control algorithms for closed-loop regulation of blood glucose levels is described. Because of the rapid response time of the BIOSTATOR Glucose Analyzer, a derivative algorithm can be applied to replace the previous generation of "predictor" algorithms for the calculation of dynamic insulin infusion rates.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

A H Clemens. 1979. Control algorithms for artificial beta cell.. https://pubmed.ncbi.nlm.nih.gov/395086/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

[The influence of blood glucose on the filtrability of red cells in diabets. Variations after connection to an artificial pancreas (author's transl)].

In 36 treated diabetics (15 with insulin, 21 with oral hypoglycaemic agents) without any detectable arterial atheromatous lesion, there was a negative correlation between the filtrability of red cells and blood glucose levels (r = - 0.60) on the one hand and, secondly, glycosylated haemoglobin levels (r = - 0.40). In 17 insulindependents diabetics connected to an artificial pancreas, normalisation of blood glucose was accompanied by a concomitant increase in the filtrability of red cells, and improvement of spontaneous platelet agregation. Good control of diabetes would thus appear to be necessary to reduce the incidence of microangiopathy.

Artificial Organs

Electrochemical determination of glucose concentration in saline solutions.

Reproducible and reliable quantitative glucose determinations in physiological solutions of saline can be obtained by using platinum powder incorporated in a thin plastic layer on a platinum wire as the test microelectrode, while applying analytic and regenerative pulses of alternating voltage of +/- 1 V (sce). The results are the beginning of further investigations leading to continuous determinations of glucose concentration in body fluids.

Artificial Organs