Search PubMed⌕ Search

PubMed · 3925505

Current algorithms for computed electron beam dose planning.

Abstract

The field of electron beam dose planning has been in a state of very rapid development during the last decade. The essentially one-dimensional manual corrections used since the beginning of the sixties, has been replaced by at least two- and sometimes three-dimensional computer algorithms capable of taking all irregularities of the body cross-section and the properties of the various tissues into account. This is achieved by dividing the incoming broad beams in a number of narrow pencil beams, the penetration of which can be described by essentially one-dimensional formalisms. The constituent pencil beams are most often described by Gaussian, experimentally or theoretically derived distributions. The accuracy of different dose planning algorithms is discussed in some detail based on their ability to take the different physical interaction processes of high energy electrons into account. It is shown that those programs that take the deviations from the simple Gaussian model into account give the best agreement with experimental results. With such programs a dosimetric relative accuracy of about 5% is generally achieved except in the most complex inhomogeneity configurations. Finally, the present limitations and possible future developments of electron dose planning are discussed.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

A Brahme. 1985. Current algorithms for computed electron beam dose planning.. https://doi.org/10.1016/s0167-8140(85)80048-7

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

[Computerized physician order entry, a tool for added safety in the hospital].

DRUG-RELATED IATROGENIC NOSOCOMIAL ILLNESS: Remains a matter of concern in the public health area. Responsibility of hospitals is challenged by the ever increasing number of patients' claims. Dysfunction in the drug-prescribing and delivery system account, to a large extent, for medication errors, some of them resulting in adverse drug events. Most generally, medication ordering by the physician is handwritten, without nominative recapitulating prescriptions, and followed by nurse transcriptions and a global medication order is transmitted to the pharmacy. This system does not integrate the pharmaceutical analysis of the prescription, before distribution of the drugs. THE COMPUTERIZED DRUG ORDER ENTRY PROCESS: The prescription is entered directly and is displayed on the computer screen, together with the previous prescriptions for the same patient. Transcription is hence eliminated. Depending on the sophistication of the software, the prescription undergoes a series of tests; warnings and reminders can be displayed online before the physician validates the prescription. Moreover, various guidelines in some aspects of drug therapy may be presented online before the prescription is completed. POSSIBILITIES: The pharmacist's access to the complete prescriptions permits analysis of the quality and safety of the prescriptions and the adequation with eventual current applicable recommendations. Prospective drug utilization review, with immediate feedback to the prescribing physician in case of concern, may be undertaken, further improving the quality of drug therapy. Moreover, a work sheet is printed out for the nurses, further enhancing the safety of drug administration and validation. The computerized drug network also permits the development of other functions. A TOOL FOR SAFETY: Currently available reports in the literature suggest that computerized drug prescription reduces the incidence of prescribing errors, improves the appropriateness of drug choices, optimises therapeutic follow-up, and reduces the incidence adverse drug events and leads to substantial reduction in drug expenditures.

Computers↗