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PubMed · 39171972

Liver transplantation for pediatric genetic and metabolic disorders.

Sara Hassan·Ahmad Anouti·Queenie K G Tan·Kirk Wangensteen·Amal Aqul
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Abstract

Pediatric genetic and metabolic liver diseases comprise a broad spectrum of conditions and represent the second most common indication for liver transplantation following biliary atresia. The decision to transplant can be challenging and requires consideration of several factors, including hepatic involvement, extrahepatic manifestations, and anticipated posttransplant outcomes. This review examines pediatric genetic and metabolic liver diseases, their pathophysiology, clinical presentation, and the role of liver transplantation.

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HumansLiver TransplantationChildLiver DiseasesTreatment OutcomeMetabolic DiseasesGenetic Diseases, InbornMetabolism, Inborn ErrorsBiliary AtresiaPatient SelectionCirrhosisCirrhotic CardiomyopathyClinical ConsiderationsDiagnostic CriteriaDiastolic DysfunctionEchocardiographyGlobal longitudinal strainPostliver transplantSystolic DysfunctionJournal ArticleReview

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Sara Hassan, Ahmad Anouti, Queenie K G Tan, Kirk Wangensteen, Amal Aqul. 2024-08-23. Liver transplantation for pediatric genetic and metabolic disorders.. https://doi.org/10.1097/lvt.0000000000000454

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