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Genomic patterns of somatic mutations provide new prognostic, therapeutic, and biological insights in cancer.

Dana Tseitline·Yuval Cohen·Sheera Adar
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Abstract

The mutational landscape of an individual's cancer can inform on its molecular state and be used as prognostic and therapeutic markers. The study by Barbour et al.1 analyzes mutational patterns in bladder cancer samples to uncover new biological insights into the ERCC2 gene function and develop new predictive prognostic tools.

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HumansMutationPrognosisUrinary Bladder NeoplasmsGenomicsXeroderma Pigmentosum Group D ProteinNeoplasmsBiomarkers, TumorJournal ArticleResearch Support, Non-U.S. Gov't

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Dana Tseitline, Yuval Cohen, Sheera Adar. 2024-08-14. Genomic patterns of somatic mutations provide new prognostic, therapeutic, and biological insights in cancer.. https://doi.org/10.1016/j.xgen.2024.100635

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