Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 3797013

Skull base chordomas.

Y P Krespi·T M Levine·R Oppenheimer
View original source ↗Export metadata ↓

Abstract

Chordomas are rare, benign tumors of the nasopharynx. Because of their location at the skull base, removal of these tumors is usually subtotal. Described is the transcervical-transmandibular approach to the skull base which can be employed in removing these tumors.

Explore related subjects

ChordomaHumansMandibleNasopharyngeal NeoplasmsNeckJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Y P Krespi, T M Levine, R Oppenheimer. 1986. Skull base chordomas.. https://pubmed.ncbi.nlm.nih.gov/3797013/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

[Protons and ions in the treatment of cancer; a systematic review of the literature].

OBJECTIVE: To provide an overview of the present role of proton and ion therapy, also referred to as 'charged particle therapy', in the treatment of cancer. DESIGN: Systematic literature study. METHOD: Systematic electronic searches were carried out in 12 databases according to the Cochrane Collaboration criteria, without restriction as to year of publication or study design. Manual searches of bibliographies and journals were also performed. The inclusion criteria were: at least 20 patients and a follow-up of at least 2 years. In addition, experts on the subject were consulted by correspondence for their opinion. RESULTS: The search identified 36 relevant articles on proton therapy and 15 on ion therapy. Based on prospective and retrospective studies, proton irradiation emerged as the treatment of choice for ocular tumours, chordomas and skull-base tumours. For prostate cancer, the results were comparable with the best results of photon therapy. Ion therapy was still in an experimental phase. CONCLUSION: According to the current literature, proton therapy is looked upon as the preferred treatment modality for certain rare tumours, such as ocular tumours, chordoma, and skull-base tumours. However, charged particle therapy as a whole, and especially ion therapy, is not supported as the treatment of choice for cancer by published evidence. Nevertheless, the potential theoretical benefit of this treatment is great.

Chordoma↗
PubMed2006

Midfacial translocation, a variation of the approach to the rhinopharynx, clivus and upper odontoid process.

OBJECTIVE: A surgical variation of the technique of facial translocation procedure is proposed, which has been called midfacial translocation for approach to the entire medial and lateral region of the middle third of the face, including the rhinopharynx, sphenoid sinus, pterygomaxillary fossa, odontoid process, and clivus. PATIENTS AND METHODS: The medical records of five treated patients accordingly were reviewed for an analysis of the surgical technique, the disease, the topography of the lesion, and the complications. RESULTS: The approach permitted ventral decompression of the bulbomedullary junction with resection of the C1 arch and the odontoid process in four patients and resection of a chordoma of the clivus located along the midline and extending intradurally in the fifth patient. Only one patient presented with dehiscence of the posterior half of the soft palate, this being the only complication observed following surgery in these patients. Three months postoperatively, no patient presented any aesthetic alteration of the face. Functionally, there was only infraorbital hypoaesthesia on the side of flap rotation. CONCLUSION: The technique of midfacial translocation provides both good surgical approach and access to the rhinopharynx, pterygomaxillary fossa, high odontoid process and clivus, with few adverse sequelae for the patient.

Chordoma↗