[Anorectal abnormalities].

R A Langemeijer; S Ekkelkamp

Home/Archive/PubMed

PubMed · 3672488

[Anorectal abnormalities].

R A Langemeijer·S Ekkelkamp

View original source ↗Export metadata ↓

Abstract

An insight in the genesis of anorectal abnormality, combined with a painstaking diagnostic examination leading to a justifiable, well-considered therapeutic procedure, may spell hope and better prospects to approximately 35 children that are born with this abnormality in The Netherlands each year. Subsequently, the function of the anorectoplasty has to be evaluated at regular check-ups. Coupled with a sound understanding of the defaecation mechanism, this should lead to uniformity in the treatment and sustenance of a child with anorectal abnormality, which will reduce the burden of this handicap for both parents and child to a minimum.

Explore related subjects

Anal Canal Anus, Imperforate Humans Infant Infant, Newborn Rectum English Abstract Journal Article

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

R A Langemeijer, S Ekkelkamp. 1987. [Anorectal abnormalities].. https://pubmed.ncbi.nlm.nih.gov/3672488/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1998

An unusual case of sexual assault on an infant: an intraperitoneal candle in a 20-month-old girl.

The recent publication of cases of sexual abuse and child prostitution networks may have the harmful effect of arousing latent desires or causing sexual delinquents to act out their impulses. The authors report a recent case in which a wax candle was introduced into the vagina of a 20-month-old baby. The forensic description is given and provisional conclusions are drawn.

Anal Canal↗

PubMed1998

[Diagnosis of the function of the anorectum and pelvic floor].

Explore the source record for details and available documents.

Anal Canal↗

PubMed1998

Virologic, immunologic, and clinical parameters in the incidence and progression of anal squamous intraepithelial lesions in HIV-positive and HIV-negative homosexual men.

Anal cancer may be preceded by anal squamous intraepithelial lesions (ASIL), but the natural history of ASIL is poorly understood. In this report, we characterize the 2-year incidence and progression of low-grade SIL (LSIL) and high-grade SIL (HSIL) in a cohort study in 346 HIV-positive and 262 HIV-negative homosexual or bisexual men. Subjects were studied at defined intervals using anal cytology, anoscopy with biopsy of visible lesions, human papillomavirus (HPV) testing, HIV serostatus, CD4 level, and data on medical history and lifestyle. The incidence of HSIL within 2 years was 20% in HIV-positive men and 8% in HIV-negative men who were normal at baseline. In total, 62% of HIV-positive and 36% of HIV-negative men with LSIL at baseline progressed to HSIL. The relative risk (RR) for anal disease progression in HIV-positive men was 2.4 (95% confidence interval [CI], 1.8-3.2) when compared with HIV-negative men. The RR increased to 3.1 (95% CI, 2.3-4.1) in HIV-positive men with CD4 counts <200/mm3. Infection with multiple HPV types was a risk factor for anal disease progression in both HIV-positive (RR = 2.0; 95% CI, 1.0-4.1) and HIV-negative (RR = 5.1; 95% CI, 2.3-11) men. The incidence of anal HSIL and progression of LSIL to HSIL within 2 years of follow-up is high in HIV-positive homosexual or bisexual men and to a lesser extent, in HIV-negative men. Men with the above risk factors may be at increased risk of developing anal cancer.

Anal Canal↗