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PubMed · 3453139

[A technic for human basophil degranulation].

S Harrabi·P Loiseau·J Dehenry
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Abstract

We had studied the human basophil degranulation test (HBDT) in 26 cases of allergic patients with drugs (penicillin, erythromycin, josamycin) one month after their anaphylactic reaction. This test was negative in 7 cases on 8 for penicillin, positive in 8 cases on 10 for erythromycin and in 6 cases on 8 for josamycin. The failure of this test with penicillin can be explained by a sensitization to a metabolic penicillin product or to the complex hapten-carrier.

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BasophilsCytoplasmic GranulesDrug HypersensitivityHelminthiasisHumansHypersensitivity, ImmediateImmunologic TestsEnglish AbstractJournal Article

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S Harrabi, P Loiseau, J Dehenry. 1987. [A technic for human basophil degranulation].. https://pubmed.ncbi.nlm.nih.gov/3453139/

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