Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 3451621

[The post-diskotomy syndrome].

J Krämer
View original source ↗Export metadata ↓

Abstract

After lumbar disc operations in some cases epidural scars develop. The symptoms consist of back- and leg pain combined with a both sided straight leg raising test. In the myelogram and CT scars can be seen. The conservative therapy can be made by local injections with steroids. A lumbosacral distraction spondylodesis with autologous bone graft can bring a certain relief. Important is a prophylaxis with the right indication for the primary disc operation: without discectomy no post-discectomy-syndrome.

Explore related subjects

CicatrixDura MaterHumansIntervertebral Disc DisplacementLumbar VertebraeMyelographyPostoperative ComplicationsSpinal FusionSyndromeTomography, X-Ray ComputedJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

J Krämer. [The post-diskotomy syndrome].. https://doi.org/10.1055/s-2008-1039696

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2003

[Gene expression in keratoconus. Initial results using DNA microarrays].

INTRODUCTION: Keratoconus is a non-inflammatory ocular disease characterised by conical deformation, progressive thinning and scarring of the central cornea. Despite intensive investigations, the exact cause of the disease still remains unclear. Clinical studies provide strong indications of a major genetic role in the aetiology. We set out to examine the involvement in the manifestation of keratoconus of any of the 5,600 gene specificities available on the Affymetrix GeneChip HuGeneFL. METHODS: After examination of two corneas they were stored in RNAlater, RNA was extracted and hybridised on the chips. Using a combination of dyes it was possible to read the chips with laser detection and to visualise the gene expression pattern. RESULTS: We found an upregulation of collagens, versican, metalloproteinases and cell adhesion proteins. A downregulation was observed for TIGR protein, cytokeratins, eyes absent homologue (Eab1) and the proteins for radical treatment selenoprotein P and monooxygenase. CONCLUSIONS: Our results indicate that keratoconus is a process in which repair and scar-formation mechanisms operate at the same time. As candidate genes for this mechanism, collagen IV and related proteoglycans were favoured.

Cicatrix↗
PubMed2003

The basic Z-plasty.

Z-plasty is a plastic surgery technique that is used to improve the functional and cosmetic appearance of scars. With this technique, it is possible to redirect a scar into better alignment with a natural skin fold or the lines of least skin tension. Contracted scars may be lengthened with this technique. Z-plasty involves the creation of two triangular flaps of equal dimension that are then transposed. Basic z-plasty flaps are created using an angle of 60 degrees on each side, which can lengthen a scar by 50 to 70 percent and reorient the direction of the central wound by 90 degrees. Keeping the length and angle of each flap precisely the same is key to avoiding mismatched flaps that may be difficult to close. Some possible complications of z-plasty include flap necrosis, hematoma formation under the flaps, wound infection, trapdoor effect, and sloughing of the flap caused by high wound tension.

Cicatrix↗
PubMed2003

[Laser surgery in dermatology. Risks and chances].

With the introduction of selective photothermolysis with pulsed laser irradiation, the quality of the dermatological laser therapy was clearly improved in the past decade. Above all the high risk of scar formation was clearly reduced. To minimize the fundamental risks that laser surgery entails such as hypo- and hyper pigmentation and scar formation, the indication should be checked precisely before any treatment. In addition, the physician must be aware of the specific side effects of the laser and its correct application. For the dermatologist, there is a wide range of indications on two levels: medical treatment of skin diseases and on the other side the use of laser technology for treatment of cosmetic-aesthetic skin disorders. Laser devices with the same effect and side effects are used for both indication groups. Thus dermatologic training should cover all laser indications.

Cicatrix↗