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PubMed · 3432429

Depression.

W R Yates
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Abstract

Depression is a prevalent and treatable psychiatric illness. Proper treatment requires accurate diagnosis, aggressive treatment, and longitudinal follow-up. The use of antidepressant medication, psychotherapy, and patient/family management techniques are discussed.

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Adjustment DisordersAntidepressive AgentsDepressive DisorderHumansMaleMiddle AgedRisk FactorsSomatoform DisordersSuicideCase ReportsJournal Article

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W R Yates. 1987. Depression.. https://pubmed.ncbi.nlm.nih.gov/3432429/

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[3H] Imipramine binding to platelets and plasma cortisol levels were measured in nine Israeli civilians before, during, and after repeated missile attacks. Hamilton Anxiety Rating Scale (HARS), and Beck Depression Inventory (BDI) were similar before and during the war and decreased significantly after the war. A trend toward increase in platelet imipramine binding values was observed during the war when compared with the postwar values (19%; p = 0.056), and/or when compared with prewar values (26%; p = 0.063). However, one-way analysis of variance with repeated measures did not reveal a significant statistical difference [F (2,6) = p = 2.07; NS] among the three time points. A significant correlation was found between HARS score, but not BDI, and imipramine binding values in the prewar and postwar time points (r = 0.87; 0.71, respectively). Plasma cortisol levels did not alter significantly during the study period.

Adjustment Disorders↗