[Pulp reactions].

A series of UV curable bioadhesives was prepared from copolymers of N-vinyl pyrrolidone with four different comonomers: 2-acrylamido methyl 1-propane sulfonic acid, vinyl succinimide, glycidyl acrylate, and 2-isocyanatoethyl methacrylate. The developed bioadhesives demonstrated a fast UV-induced setting with a set time of about 3 min. Bond strength between the bioadhesive and porcine intestine specimen was determined by the peel test. These bioadhesives can provide improved adhesion values up to 4.6 N/m of 180 degrees peel strength compared to five different commercial bioadhesives (values ranging from 0.52 to 3.04 N/m). In addition, the fully hydrated UV curable bioadhesives have shown a high water uptake ranging from 25 to 350 wt% and equilibrium water content ranging from 20 to 100 wt%. Because N-vinyl pyrrolidone is a monomer all these copolymers are expected to retain good biocompatibility. Obtained promising results of peel strength and water uptake clearly suggest that the developed bioadhesives have a strong potential for many medical applications such as single-layered hydrogel wound dressings and tissue adhesives.

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PubMed1997

Chemical and biological evaluation of proteins and mucilages from roots and seeds of Glossostemon bruguieri Desf. (Moghat).

The powdered roots of moghat (Glossostemon bruguieri) have been traditionally used in Eastern countries for their nutritive and therapeutic value. However, the biological effects of the plant constituents have not been proved on the basis of scientific research. The present study aimed to evaluate the content and composition of proteins and mucilages of the roots and seeds of moghat, as well as the hypoglycemic effect of the mucilages. The crude protein constituted 19.5% of the seeds, while it made up 4.5% of the peeled dried roots of Glossostemon bruguieri (Moghat). Glutamic acid, proline, leucine, phenylalanine, histidine and arginine were abundant in the protein of both plant parts; 72 and 83%, respectively. Valine, cysteine, methionine and lysine were detected only in seed protein. Molecular weights of the seed proteins were 50,000, 45,000 and 22,000. Moghat seeds contained 5.0% mucilage, while 15.75% and 29.60% were recorded in roots of one- and two-year-old plants, respectively. GLC investigation showed that both these plant parts contained rhamnose, xylose, mannose and galacturonic acid. Arabinose (1.8%) and glucuronic acid (14.6%) were present only in the seeds, while galactose constituted 33.7 to 34.5% of the root mucilage. Age of the roots was reflected in quantitative differences rather than qualitative ones. The root mucilages had remarkable hypoglycemic activity, decreasing the blood glucose level in diabetic rats by 54.5% within 15 days. Accordingly, moghat roots should be investigated as potential medical and nutritive food.

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