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PubMed · 3269840

[Running use and the decrease of effect of a disinfectant for dental instruments].

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K Sakata, R Ishikawa, T Chiba, H Baba. 1988. [Running use and the decrease of effect of a disinfectant for dental instruments].. https://pubmed.ncbi.nlm.nih.gov/3269840/

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Interaction between N-dodecyl-N,N-dimethyl-N-benzylammonium halides and phosphatidylcholine bilayers-the effect of counterions.

The interaction of N-dodecyl-N,N-dimethyl-N-benzylammonium halides (DBeAX) with two types of phospholipid vesicles (MLV and SUV) was investigated using DSC and 1H NMR. It was suggested that the benzyl group like the micellisation process (J. Colloid Interface Sci. 218 (1999) 529) changes its position when interacting with phosphatidylcholine bilayers and incorporates into the bilayer. In order to enhance counterion-water interactions, the surfactants were added either to the water phase or directly to the lipid phase (a mixed film was formed). It follows from the obtained results that for both types of liposomes and both manners in which the surfactant was added, the interaction of DBeAX with liposomes and consequent changes in the phospholipid bilayer organisation depend on the kind of counterion. Results are discussed in terms of counterion ability to modify water structure.

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