Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 3048855

Urinary parameters to assess renal function.

J R Diamond·M L McLaughlin
View original source ↗Export metadata ↓

Abstract

Acute suppression of renal function has a multitude of etiologies. This review discusses the pathophysiologic basis, usefulness, and limitations of the commonly utilized urinary function parameters as well as some miscellaneous tests to properly diagnose specific disorders.

Explore related subjects

CreatinineHumansKidney DiseasesKidney Function TestsNatriuresisOsmolar ConcentrationSpecific GravityUrineJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

J R Diamond, M L McLaughlin. 1988. Urinary parameters to assess renal function.. https://pubmed.ncbi.nlm.nih.gov/3048855/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2002

A randomised controlled trial investigating the effects of dopexamine on gastrointestinal function and organ dysfunction in the critically ill.

OBJECTIVE: To determine whether an infusion of dopexamine for up to 7 days has an effect on gastrointestinal (GIT) absorption and permeability, renal function or organ dysfunction in the critically ill. DESIGN AND SETTING: Prospective, randomised controlled clinical trial in two general adult intensive care units. PATIENTS: 102 critically ill adult patients predicted to require organ support for at least 4 days. INTERVENTIONS: After resuscitation patients were randomly assigned to receive an infusion of up to 2 mcg/kg/min [corrected] per minute of dopexamine or control. MEASUREMENTS AND RESULTS: GIT absorption and permeability were measured using the ratio of absorbed rhamnose to 3- O-methyl- D-glucose and the ratio of lactulose to rhamnose on days 1, 4 and 7. Creatinine clearance was measured concurrently. Daily Sequential Organ Failure Assessment scores were calculated. Fifty-two patients received dopexamine. No significant difference between the two groups emerged on any of the measured parameters during the study period. CONCLUSIONS: No benefit was seen from a prolonged infusion of dopexamine in this group of critically ill patients in terms of GIT absorption and permeability, creatinine clearance or organ dysfunction.

Creatinine↗