Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 2823402

Ischemic neuropathy.

B E Cahill·M D Kerstein
View original source ↗Export metadata ↓

Abstract

Several medications can be used to treat patients with painful diabetic neuropathy. However, studies differ as to the efficacy of many of these agents. We hope future research will help to delineate a more exact usage of these agents in the treatment of this condition. Ischemic neuropathy as it pertains to arteriosclerosis, thromboangiitis obliterans and diabetes mellitus has been discussed in this study. The vascular anatomy of peripheral nerves has been presented. Furthermore, research has been discussed that shows diffuse ischemic results in nerve demyelination and axonal degeneration. It is hoped that this report will help to delineate the incidence and significance of ischemic neuritis in patients with peripheral vascular occlusive disease.

Explore related subjects

Arteriosclerosis ObliteransChronic DiseaseDiabetic AngiopathiesDiabetic NeuropathiesHumansIschemiaMalePeripheral NervesPeripheral Nervous System DiseasesThromboangiitis ObliteransJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

B E Cahill, M D Kerstein. 1987. Ischemic neuropathy.. https://pubmed.ncbi.nlm.nih.gov/2823402/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

[Buchwald's operation in the surgery of atherosclerosis obliterans].

Analyzing the world's experience in the surgical management of hyperlipidemias and their own results, the authors make an assessment of Buchwald's operation used in the surgery for atherosclerosis obliterans. The major disadvantage of partial ileac bypass is that there is no prognosis of the operation and its complication. Based on the pathophysiological mechanisms of implementation of Buchwald's operation, the authors have developed a mode of pharmacological simulation of a partial bypass which allows one to predict the effect of the impending intervention and to avoid unjustified operations. The unique procedure also enables the indications for simultaneous interventions to be defined. Ten partial ileac bypass surgeries made by the authors are comprehensively analyzed. Taking into account, the authors propose to choose a treatment of patients with hyperlipidemia and atherosclerosis on an individual basis and to do away with the routine indications for partial ileac bypass surgery.

Arteriosclerosis Obliterans↗
PubMed1992

Hematologic changes in type 2 diabetic patients with various localizations of peripheral vascular disease.

Some hematologic parameters have been measured in 80 patients with Type 2 diabetes mellitus. The patients were divided into three groups: (a) proximal (pelvic and femoral) lower limb macroangiopathy; (b) distal (tibial) macroangiopathy; and (c) control group of diabetics without lower limb macroangiopathy. Mean hemoglobin, hematocrit and fibrinogen values were significantly higher in both the proximal and distal macroangiopathy groups in comparison with the controls. On the other hand, mean leucocyte and platelet counts were significantly elevated only in the proximal macroangiopathy group. Significant correlations were observed in univariate and multivariate analyses between blood fibrinogen concentration and pressure indices expressing severity of lower limb macroangiopathy (ankle/thigh, ankle/arm). In summary, increased levels of hematologic parameters contributing to the increase of whole blood viscosity were observed in Type 2 diabetics with arteriosclerosis obliterans. The observed relationship between fibrinogen concentration and severity of arteriosclerosis obliterans could be an evidence in favor for fibrinogen lowering therapy in this pathologic condition.

Arteriosclerosis Obliterans↗