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PubMed · 2632977

[Relation between optic disk changes and visual fields and the outflow coefficient values in primary glaucoma].

Abstract

On the basis of archival records of 1463 patients the author isolated the cases of primary open angle glaucoma (2248 eyes) and closed angle glaucoma (333 eyes). The influence of the outflow factor on the grade of damage of nervous fibres manifesting itself by changes in the optic disc and abnormalities of the visual field was analyzed. It showed that this influence was statistically significant especially in cases of closed angle glaucoma.

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Z Skrzymowska. 1989. [Relation between optic disk changes and visual fields and the outflow coefficient values in primary glaucoma].. https://pubmed.ncbi.nlm.nih.gov/2632977/

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Expression of factor VIII-related antigen in human aqueous drainage channels.

PURPOSE: Previous studies have indicated that there are preformed channels at the inner aspect of the anterior sclera, capable of draining fluid from the suprachoroidal space into scleral veins. The aim of this study was to characterize the cellular lining of these channels, and to compare it with the endothelium of Schlemm's canal, the collector channels and the scleral blood vessels. METHODS: Histological sections from the angular region of human eyes were prepared by an immunoperoxidase method to evaluate the expression of factor VIII-related antigen in different aqueous drainage channels. RESULTS: The cellular lining of the scleral channels showed a weak immunostaining to factor VIII-related antigen. Factor VIII-related antigen was also detected in the endothelium of the collector channels and Schlemm's canal. CONCLUSION: The positive immunoreaction to factor VIII-related antigen indicates that the previously described scleral channels, the collector channels and Schlemm's canal are all lined by an endothelium derived from a vascular origin.

Aqueous Humor