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PubMed · 2620751

Decrease of ultraviolet-induced DNA injury in human skin by p-aminobenzoic acid esters.

S De Rijcke·M Heenen
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Abstract

The effect of a sunscreen containing a p-aminobenzoic acid (PABA) ester on ultraviolet-induced DNA injury was assessed on human epidermal cells by the measure of unscheduled DNA synthesis intensity. Our results show that DNA repair was reduced by approximately 50%. Therefore, sunscreens based on PABA esters might be expected to reduce photocarcinogenesis.

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4-Aminobenzoic AcidAutoradiographyDNADNA DamageDNA RepairDNA ReplicationHumansSkinThymidineUltraviolet RaysJournal Article

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S De Rijcke, M Heenen. 1989. Decrease of ultraviolet-induced DNA injury in human skin by p-aminobenzoic acid esters.. https://doi.org/10.1159/000248359

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Simultaneous determination of p-aminobenzoic acid and its metabolites in the urine of volunteers, treated with p-aminobenzoic acid sunscreen formulation.

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